Administration of AGEs in vivo induces extracellular matrix gene expression
نویسندگان
چکیده
منابع مشابه
Extracellular Matrix Influences on Gene Expression
cialist working in the area under discussion or to individuals involved in very closely related areas of research. Within these limits, both the clinical and basic immunologist will find the first of two of these articles to be extremely useful, while immunochemists will no doubt value all three. The study of histocompatibility antigens is becoming increasingly important since apart from their ...
متن کاملBiomimetic extracellular matrix-incorporated scaffold induces osteogenic gene expression in human marrow stromal cells.
Engineering biomaterials mimicking the biofunctionality of the extracellular matrix (ECM) is important in instructing and eliciting cell response. The native ECM is highly dynamic and has been shown to support cellular attachment, migration, and differentiation. The advantage of synthesizing an ECM-based biomaterial is that it mimics the native cellular environment. However, the ECM has tissue-...
متن کاملExtracellular matrix gene expression in the developing mouse aorta
3. The vascular ECM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84 3.1. C ollagens . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86 3.2. E lastic fiber proteins . . . . . . . . . . . . . . . . . . . . . . . . . 86 3.3. F ibronectin . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87 3.4. B asement membrane components. . . . . . . . . . . . . . . . . . 87...
متن کاملExtracellular matrix-induced gene expression in human breast cancer cells.
Extracellular matrix (ECM) molecules modify gene expression through attachment-dependent (focal adhesion-related) integrin receptor signaling. It was previously unknown whether the same molecules acting as soluble peptides could generate signal cascades without the associated mechanical anchoring, a condition that may be encountered during matrix remodeling and degradation and relevant to invas...
متن کاملExtracellular matrix regulates expression of the TGF-beta 1 gene
Transforming growth factor-beta (TGF-beta) is a potent regulator of cell proliferation and modulates the interactions of cells with their extracellular matrix (ECM), in part by inducing the synthesis of various ECM proteins. Three different isoforms of TGF-beta are synthesized in a defined pattern in specific cell populations in vivo. In the specific case of TGF-beta 1, this well-defined and li...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 1996
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/11.supp5.62